Emily Stern, M.D.

Site-Specific Project Principal Investigator, Brigham and Women's Hospital

Emily Stern, M.D. directs the Functional Neuroimaging Laboratory (FNL) with Dr. David Silbersweig at Brigham and Women's Hospital. Dr. Stern attended Amherst College and obtained her medical degree from Cornell University Medical College. After completing her internship in Internal Medicine and residency in Diagnostic Radiology at New York Presbyterian Hospital, she pursued advanced training in functional neuroimaging at the MRC Cyclotron Unit at the Hammersmith Hospital in London, U.K. She then returned to the U.S. to found the FNL with Dr. Silbersweig at Cornell in 1994. In 2008, Drs. Stern, Silbersweig, and the FNL moved to Brigham and Women's Hospital, Harvard Medical School.

Dr. Stern oversees all aspects of studies performed in the FNL. Translational models, focusing on fronto-limbic function, are used as a basis for the identification and characterization of abnormal patterns of distributed neural activity underlying symptom formation in major psychiatric disorders, using advanced neuroimaging techniques. Schizophrenia (psychosis), affective disorders, anxiety disorders, personality disorders and other neuropsychiatric diseases are studied, as are neural circuitry differences between the sexes in this context. In addition, there is an emphasis on the development of new imaging and analysis methods to study these disorders with greater sensitivity, specificity and resolution.

In addition to her role in the FNL, Dr. Stern is the Director of the fMRI Program, and Director of Functional and Molecular Neuroimaging at BWH.


Recent Publications:

Butler T, Weisholtz D, Isenberg N, Harding E, Epstein J, Stern E, Silbersweig D. Neuroimaging of frontal-limbic dysfunction in schizophrenia and epilepsy-related psychosis: Toward a convergent neurobiology. Epilepsy Behav. 2012 Feb; 23(2):113-22.

Epstein J, Perez DL, Ervin K, Pan H, Kocsis JH, Butler T, Stern E, Silbersweig DA. Failure to segregate emotional processing from cognitive and sensorimotor processing in major depression. Psychiatry Res. 2011 Sep 30; 193(3):144-50.

Rigolo L, Stern E, Deaver P, Golby AJ, Mukundan S. Development of a clinical functional magnetic resonance imaging service. Neurosurg Clin N Am. 2011 Apr; 22(2):307-14, x.

Vago DR, Epstein J, Catenaccio E, Stern E. Identification of neural targets for the treatment of psychiatric disorders: the role of functional neuroimaging. Neurosurg Clin N Am. 2011 Apr; 22(2):279-305, x.

Pan H, Epstein J, Silbersweig DA, Stern E. New and emerging imaging techniques for mapping brain circuitry. Brain Res Rev. 2011 Jun 24; 67(1-2):226-51.

Chen H, Epstein J, Stern E. Neural plasticity after acquired brain injury: evidence from functional neuroimaging. PM R. 2010 Dec; 2(12 Suppl 2):S306-12.

Tuescher O, Protopopescu X, Pan H, Cloitre M, Butler T, Goldstein M, Root JC, Engelien A, Furman D, Silverman M, Yang Y, Gorman J, LeDoux J, Silbersweig D, Stern E. Differential activity of subgenual cingulate and brainstem in panic disorder and PTSD. J Anxiety Disord. 2011 Mar; 25(2):251-7.

Root JC, Tuescher O, Cunningham-Bussel A, Pan H, Epstein J, Altemus M, Cloitre M, Goldstein M, Silverman M, Furman D, Ledoux J, McEwen B, Stern E, Silbersweig D. Frontolimbic function and cortisol reactivity in response to emotional stimuli. Neuroreport. 2009 Mar 4; 20(4):429-34.